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Do Fat Burner Supplements Actually Work?

Thomas DeLauer

Thomas DeLauer

Published on 10 months ago

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Do Fat Burner Supplements Actually Work? - Thomas DeLauer

Catecholamines play a key role in nutrient metabolism and the generation of body heat, aka thermogenesis

They stimulate not only oxygen consumption but also consumption of fuels, such as glucose and free fatty acids, thereby generating heat

They stimulate glycogenolysis and the breakdown of triglycerides, the stored form of fat, to free fatty acids (lipolysis)

Study - Journal of the International Society of Sports Nutrition

Researchers looked at the effects of a fat loss supplement on resting metabolic rate and hemodynamic variables in resistance-trained males

10 resistance-trained male participants underwent two testing sessions separated by at least 24 hours

On their first visit, participants arrived to the laboratory after an overnight fast and a 24 hour avoidance of exercise, and underwent a baseline RMR, HR, and BP assessment

Next, each participant ingested a thermogenic fat loss supplement (TFLS) or a placebo (PLA) and repeated the RMR, HR, and BP assessments at 60, 120, and 180 min post-ingestion

During the second visit the alternative supplement was ingested and the assessments were repeated in the exact same manner


The thermogenic fat loss supplement (Iron Cuts) treatment and placebo were ingested in capsule form, and three capsules were ingested per dose

Capsules were identical in appearance and taste, and the ingredients in the thermogenic fat loss supplement treatment were:

L-Carnitine Tartrate, Green Tea Leaf Extract, Caffeine Anhydrous, Panax Ginseng Root Powder, N-Acetyl-L-Tyrosine, Thermodiamine™ (98 % Evodiamine), Vinpocetine, Inositol.

The placebo contained only inert ingredients (650 mg of maltodextrin and 88.8 mg of hemp protein)


TFLS significantly increased RMR at 60-min, 120-min, and 180-min post ingestion as compared to baseline RMR values

No significant changes in RMR were observed for the PLA treatment

Specifically, RMR was increased by 7.8 % (from 1,906 to 2,057 kcal), 6.9 % (from 1,906 to 2,037 kcal), and 9.1 % (from 1,906 to 2,081 kcal) in the TFLS, while the PLA treatment increased RMR by 3.3 % (from 1,919 to 1,981 kcal), 3.1 % (from 1,919 to 1,978 kcal), and 2.1 % (from 1,919 to 1,959 kcal) above baseline at 60, 120, and 180-min post ingestion, respectively

Additionally, the TFLS significantly elevated RMR at the 3-hour time point as compared to the PLA treatment (2,081 vs 1,959 kcal)

A main effect for groups was observed for systolic blood pressure, and a significant interaction and main effect for time were observed for diastolic blood pressure

It should be noted that although changes in diastolic blood pressure were significant, all values stayed within normal clinical ranges (less than 80 mmHg)

Concluded that the fat burner led to significant elevations in RMR as compared to baseline, and that these elevations came with no adverse effect relative to resting heart rate, but a slight increase in blood pressure values

So taken on a daily basis, the fat burner may increase an individual’s overall energy expenditure


*A meta-analysis published in the journal Appetite 20 of which were selected for inclusion, involving 563 participants looked at capsaicin in the potential role for weight management

that consumption of capsaicinoids increases energy expenditure by approximately 50 kcal/day, and that this would produce clinically significant levels of weight loss in 1-2 years


Fat burners are designed to have a thermic effect on the body, causing your resting RMR to increase - the idea is that they’re additional calories being burned without the additional work,

However, it’s unclear whether this effect leads to significant weight loss or reductions in body fat in the long run - likely would, but chronic use would be required


1) Jeukendrup AE and Randell R. (n.d.). Fat burners: nutrition supplements that increase fat metabolism. - PubMed - NCBI. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/21951331
2) The effects of a fat loss supplement on resting metabolic rate and hemodynamic variables in resistance trained males: a randomized, double-blind, placebo-controlled, cross-over trial. (n.d.). Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818444/
3) Whiting S , et al. (n.d.). Capsaicinoids and capsinoids. A potential role for weight management? A systematic review of the evidence. - PubMed - NCBI. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/22634197
4) Thermogenesis - an overview | ScienceDirect Topics. (n.d.). Retrieved from https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/thermogenesis

Comments :

lou milano

lou milano . 10 months ago

The reason I'm a devout follower of thomas delauer is because of his amazing and mind blowing content!!! I'm in the best shape and health of my life at 50 years old because of him!!! Thomas keep the content coming because I'm a human sponge brother!!!


JEFF WESBROOKS . 1 week ago

Thank you for this video. You saved me money!! Now I’m not wasting my money!!

K Edmodson

K Edmodson . 2 weeks ago

You don;t need any of this shite. Losing weight is easy, stop putting shit in your mouth and exercise more. Works for me. No way would i fill my body full of this rubbish, it isn’t needed.


DjBacto . 2 weeks ago

Love watching your content

Ben L

Ben L . 2 weeks ago

jesus f christ you talk like an actual scientist its making my adrenal glands, opioid glands, and testicular glands extremely sore ffs

Swapnil Upadhyay

Swapnil Upadhyay . 2 weeks ago

Can we take fat burners during intermittent fasting ? Request your views on this

Zabrina Divine

Zabrina Divine . 3 weeks ago

I think I'm more amazed at how smart this man sounds then the content lol very informational tho👏

E -

E - . 3 weeks ago

They market all kind of crazy things including making people think they aren’t using steroids. Its disheartening.

Nady singh [Bult wala munda]

Nady singh [Bult wala munda] . 3 weeks ago

I don't understand your English so please write here that should we take fat burner or not? One more thing MDN keto fat burner is safe or not ?


SanDiegoFreddy . 3 weeks ago

I guess the fat burner I just ordered is going back to Amazon. Coffee will continue to fuel my workout. Thanks for the video.

CPA marketingacademy

CPA marketingacademy . 3 weeks ago

Answer not worth it.... this video could easily be 1 minute. 🤔can't trust this guy. He uses a bunch of useless words to look cool and scientific, when the answer is a lot more simpler. Note: fuck you SCAMMER.


Gerardo . 4 weeks ago

Y'all came for 10:40 😁


WARRIORSTEAK . 1 month ago

Hey thomas!! I love your videos....thank you....but I wanna know does taking fat burners disrupt a fast? I do the 16/8.


vpngor . 1 month ago

Let’s Get Well Paperback – Import, 21 Aug 1995 by Adelle Davis (Author) 4.6 out of 5 stars 94 ratings , pages 464, language – English.. : https://amzn.to/2NmxloJ

Adio Ash

Adio Ash . 1 month ago

Well I’ll try it because I don’t drink coffee or any caffeinated drinks. Any particular ones you would recommend?

Ano Nymous

Ano Nymous . 1 month ago

Fat burners actually works. This one works. Try it for yourself and you will see. Free shipping & 50% off for first time customer: ​https://www.alkatone.com/v10/?AFFID=1138&C1=13281&C2=&C3=10286b9ee32638850e7453d9ff2e32&click_id=5e1f22e6-844f-4b79-b721-cfb7c7b469e6&OPT=

David Evans

David Evans . 1 month ago

Lol Gazebo Group 😂

tuấn phạm anh

tuấn phạm anh . 2 months ago

Dude, u just blow my mind . find my self really interested with this examiner. Thanks for very effective vids. Keep it up .

Vinny LT

Vinny LT . 2 months ago

Thank you for doing this video with a shirt on and speaking at a normal volume unlike so many scrubs out there.

sumon mahmud

sumon mahmud . 2 months ago

oh, what a useful video it is . thanks a lot for share this with us. i know about a supplyment which is very effective.you can check it here https://amzn.to/35O14xU


D A . 2 months ago

Adrenaline IS epinephrine...

Christian Newbern

Christian Newbern . 2 months ago

The best place to lose a lot of weight in a healthy safe way is here i did it and changed my life was able to accomplish things i never thought i would ever be able to do thx to this sight really is a blessing i tell no lie this is the best http://bit.ly/WEIGHTLOSSFATBURN


Windsjorn . 2 months ago

So basically to summarize: "They do work but are not a miracle supplement and requires you to be actively exercising in order to for it to work correctly. They are not meant to be used for people who are just going to pop them in their mouth, then sit around all day.

Sword champ KNG Bhachka Sourov hlla. Gangopadhya 2

Sword champ KNG Bhachka Sourov hlla. Gangopadhya 2 . 2 months ago

Your tips are good ,some food burn supplement name do share to my facebook Instagram ,I am -Sourov KNG Ganguly (2).


HnH . 2 months ago

I have no clue what 25% of the words he said and because of that, this guy knows what he is talking about.

Tiffanie Matteson

Tiffanie Matteson . 2 months ago

Just discovering your videos in the last month and I’ve been really enjoying them !

Luke Galo

Luke Galo . 2 months ago

Fat burner capsule won't work if you don't GYM or exercise😊


alexisgc33 . 3 months ago

Thank so much for the video and all the great info. I'm a 36 male, trying lean out. I'm 5'10 and currently 160 (down from 187lbs). I want to lean out to 145-140 (I don't want to get huge, just lean). I don't drink coffee at all. Is the caffeine in the pre-workout enough to act like coffee? Or would using fat burners help ? Currently tracking my food and eating 145p 140c 50f per day.

Roger Perez

Roger Perez . 3 months ago

kinobody is a bitch fake ass

richard r

richard r . 3 months ago

Ok den what?

Domingo Reyes

Domingo Reyes . 3 months ago

I dont like coffee, so should I get a powder fat burner, like hydroxycut? Please help

ruru_ esco

ruru_ esco . 3 months ago

Basically just good old fashion work outs are the best way to go..

Cass Cassy

Cass Cassy . 4 months ago

DON'T ever waste your time or money on Fatburners. Expensive urine


7Vibes2Passion . 4 months ago

My opinion: Just mix all the ingredients together and put it in size 00 capsules. Capsaicin, fresh black pepper, tumeric & cinnamon. This will increase your body temperature and burn fat.

Marius Neagoe

Marius Neagoe . 4 months ago

Go buy that Thermo-X by Myprotein niggaz! Best on the market by far!

Marius Neagoe

Marius Neagoe . 4 months ago

Hell no! If you watch all this you gon' spend more time on YT than in the gym 🚫🧢😤 just say yes or no fuck! Off course fat burners are great y'all should pop that shit if you are a beginner to lose that fat that you are bor with.

johnny gladstone

johnny gladstone . 4 months ago

This guy is an idiot.


CaptSmallTalk . 4 months ago

Thomas, we appreciate all you do but some of us would rather not get into the science of it all and would prefer a much more brief explanation. Possibly in a smaller video. Thank you for the videos.

Bring The Rain

Bring The Rain . 4 months ago

I'm not even gonna watch this because I know what he's gonna say about fat burners... It's all business and he's not going to tell you something that goes against what he promotes for a living...

Himanshu Kanojia

Himanshu Kanojia . 4 months ago

Lol but my fat burner has all the ingredients that you endorse . L carnitine , greet tea extract , caffeine , green coffee extract

Edward Chavez

Edward Chavez . 4 months ago

So technically they do work since caffeine is what does the magic and most fat burning pills have caffeine.

Subina Vlogs

Subina Vlogs . 4 months ago

if you are impatient like me then here’s the bottom line of the story Fat burners doesn’t work!!

The Bitter Tech

The Bitter Tech . 4 months ago

As suggested in the video - I'm working out intensely 4 times a week, I would like to try a quality thermo to see it's effects. Any suggestions?

Richard Bacon

Richard Bacon . 4 months ago

Thomas, you state that L carnitine isnt really effective yet in another vid you advocate adding it to a pre work out drink with beta alanine and citrulline malate...is it effective or not?

Primož Cerar

Primož Cerar . 4 months ago

Coffe better😀. Food supliments are never good for body. Just the right food and some workout. Or some cycling, walking and running. And i think your good. Just need pacient for resaults. Took me 1 year to lost 30kg.

mystical penguin3000

mystical penguin3000 . 5 months ago

Natural will always be better than any supplement


Mudig . 5 months ago

my fat ass generates heat on its own.

Jan Andy

Jan Andy . 5 months ago

I at first obtained this amazing cholesterol guidebook “Hοzantο Axy” (Google it) to help lower my "bad" cholesterol and also increase my "good" cholesterol. I am confused if it is carried out like that way. Since I haven’t tried it for that reason I don’t have a clue if this one works well. I can`t wait to get my cholesterol level examine again in a few weeks. Based on all the things I have read, this should really help. .

Richmond KE

Richmond KE . 5 months ago

Is animal cuts best for fat burning

kavish sharma

kavish sharma . 5 months ago

Tell me yes /or/no

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